منابع مشابه
Effects of Alprazolam on Cortical Activity and Tremors in Patients with Essential Tremor
BACKGROUND Essential tremor (ET) is characterised by postural and action tremors with a frequency of 4-12 Hz. Previous studies suggest that the tremor activity originates in the cerebello-thalamocortical pathways. Alprazolam is a short-acting benzodiazepine that attenuates tremors in ET. The mechanisms that mediate the therapeutic action of alprazolam are unknown; however, in healthy subjects, ...
متن کاملZonisamide for essential tremor.
OBJECTIVE The pharmacological therapy for essential tremor (ET) is inadequate, and many patients resort to surgical procedures. Zonisamide is an antiepileptic with several potential mechanisms of action. MATERIALS AND METHODS We evaluated zonisamide for ET in an open-label pilot trial. The primary efficacy point was the change in the Tremor Study Group rating scale (TSGRS) scores. RESULTS T...
متن کاملEssential tremor
Methods Seventy-two patients with severe, medication-refractory essential tremor have been enrolled across seven international centers. Standard assessments of tremor severity and disability will be obtained before and after the procedure. Patients are randomized in a one-to-three fashion to receive either sham procedure or MR-guided focused ultrasound thalamotomy. The Tremor Research Group, ne...
متن کاملKnowledge about Essential Tremor: A Study of Essential Tremor Families
Background Essential tremor (ET) is among the most common neurological diseases and it often runs in families. How knowledgeable ET patients and their families are about their disease has been the subject of surprisingly little scholarship. Methods To fill this gap in knowledge, we administered a comprehensive 32-item survey (i.e., questions about etiology, pathophysiology, symptoms and signs...
متن کاملTremor-correlated cortical activity in essential tremor.
BACKGROUND In patients with parkinsonian resting tremor, tremor-correlated activity in the contralateral sensorimotor cortex has been studied by both magnetoencephalography (MEG) and electroencephalography (EEG). In essential tremor, MEG failed to detect cortical involvement. The objective of this study was to investigate whether EEG recording can reveal tremor-correlated cortical activity in p...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2015
ISSN: 1465-1858
DOI: 10.1002/14651858.cd009681.pub2